产品介绍 |
Amylin is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta amyloid (Abeta) assosciated with Alzheimer's disease, can induce apoptotic cell death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
胰岛淀粉样肽(islet amyloid polypeptide,IAPP)又称amylin 或糖尿病相关肽是由胰腺β细胞产生的一种短肽。IAPP降低胰岛素的敏感性,抑制肌肉组织中葡萄糖的摄取和糖原的合成,抑制病人摄取食物
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