| 产品编号 | bs-0467P |
| 英文名称 | Ghrelin Antibody Blocking Peptide |
| 中文名称 | 脑肠肽封闭多肽 |
| 别 名 | Appetite regulating hormone; Ghrelin 27; Ghrelin 28; Ghrelin/obestatin prepropeptide; GHRL; Growth hormone releasing peptide; Growth hormone secretagogue; M46 protein; Motilin related peptide; MTLRP; Obestatin; Obestatin preprohormone; PRO1066; UNQ524; GHRL_HUMAN. |
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Specific References (2) | bs-0467P has been referenced in 2 publications.
[IF=2.784] Liu et al. Ghrelin protects the myocardium with hypoxia/reoxygenation treatment through upregulating the expression of growth hormone, growth hormone secretagogue receptor and insulin-like growth factor-1, and promoting the phosphorylation of protein kinase B. (2018) Int.J.Mol.Med. 42:3037-3047 WB&IHC ;
[IF=1.741] Yang Juesheng. et al. Protective effect of inhibiting TRPM7 expression on hypoxia post-treatment H9C2 cardiomyocytes. Clin Hemorheol Micro. 2021 Jan;77(1):91-105
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| 理论分子量 | kDa |
| 检测分子量 | |
| 性 状 | Lyophilized |
| 物 种 | human |
| 纯化方法 | 1 |
| 活性 | Not tested |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 产品介绍 |
This gene encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Obestatin was initially reported to be an endogenous ligand for the orphan G protein-coupled receptor GPR39 and was involved in satiety and decreased food intake; however, these findings are controversial. Recent reports show that obestatin is involved in inhibiting thirst and anxiety, improving memory, regulating sleep, affecting cell proliferation, and increasing the secretion of pancreatic juice enzymes. Alternative promoters and alternative splicing result in multiple transcript variants, some of which encode different protein isoforms and some of which do not encode a protein but may regulate the ghrelin-obestatin preproprotein expression. In addition, antisense transcripts for this gene have been identified and may also function in regulation of the ghrelin-obestatin preproprotein expression. [provided by RefSeq, Oct 2008]. Ghrelin是近年来发现的一种内源性生长激素促分泌剂受体的配体。 广泛分布在人中枢神经系统(下丘脑、垂体)和消化系统(胃、肠、胰腺),并被发现拥有多种生物功能,如通过下丘脑刺激食欲、增加胃酸分泌、提高胃肠蠕动等.进而ghrelin和GHS-R在不同器官肿瘤组织中被发现,如垂体瘤、胃癌、肠癌、乳腺癌、甲状腺滤泡状癌。 研究证明ghrelin能影响不同肿瘤细胞的生长与增殖.其广泛的生物活性为今后肿瘤的诊断、治疗及预后的评估提供了新的研究方向. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
