产品编号 |
bs-0855P |
英文名称 |
Recombinant human Insulin
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中文名称 |
重组人胰岛素蛋白 |
别 名 |
ILPR; INS; Insulin A chain; Insulin B chain; Insulin A chain; Insulin precursor; IRDN; Proinsulin; Proinsulin precursor; IDDM2; INS_HUMAN; MODY10 |
克 隆 号 |
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理论分子量 |
5.8 kDa |
检测分子量 |
6 |
性 状 |
Lyophilized |
物 种 |
Human |
序 列 |
1-110/110 |
纯 度 |
>95% as determined by SDS-PAGE |
纯化方法 |
AC |
内毒素 |
<1.0 EU/μg as determined by endotoxin. |
表达系统 |
Yeast |
活性 |
Not tested |
标签 |
Tag free |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
Recombinant full length human Insulin; 51 amino acids, 5807 Dalton.
Serum-free medium supplements such as insulin are essential for long-term growth of commonly used mammalian cell lines. When insulin is absent from media, cell may exhibit disturbances in morphology and growth rate. Insulin, recombinant human (rHu) is identical in function and structure to the native human sequence. A hormone consisting of two polypeptide chains, rHu Insulin′s A-chain (21 amino acids) and B-chain (30 amino acids) are covalently linked by disulfide bonds between cysteine residues. This genetically engineered human insulin is a full sequence molecule producted by recombinant DNA technology in baker′s yeast. Two-chain polypeptide hormone produced by the Beta-cells of pancreatic islets. Its molecular weight is ~5800 Da. The Alpha and Beta chains are joined by two interchain disulfide bonds. The Alpha chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.
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产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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