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Rabbit Anti-Growth Arrest Specific Protein 7  antibody (bs-4279R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-4279R
英文名称 Rabbit Anti-Growth Arrest Specific Protein 7  antibody
中文名称 生长休止特定蛋白7抗体
别    名 GAS 7; GAS-7; Gas7; GAS7_HUMAN; Growth arrest specific 7; Growth arrest-specific protein 7; KIAA0394; MGC1348; MLL/GAS7; MLL/GAS7 fusion protein.  
研究领域 肿瘤  细胞生物  免疫学  染色质和核信号  信号转导  细胞周期蛋白  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 54kDa
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GAS7/Growth Arrest Specific Protein 7: 361-476/476 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Growth arrest specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. It may play a role in neuronal development by promoting maturation and morphological differentiation of cerebellar neurons. Several transcript variants encoding proteins which vary in the N terminus have been described.

Function:
May play a role in promoting maturation and morphological differentiation of cerebellar neurons.

Subcellular Location:
Cytoplasm (By similarity).

DISEASE:
Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX.

Similarity:
Contains 1 FCH domain.
Contains 1 SH3 domain.
Contains 1 WW domain.

SWISS:
O60861

Gene ID:
8522

Database links:

Entrez Gene: 8522 Human

Omim: 603127 Human

SwissProt: O60861 Human

SwissProt: O55148 Rat

Unigene: 258855 Human

Unigene: 462214 Human

Unigene: 17160 Rat



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