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Rabbit Anti-MPP6  antibody (bs-5756R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-5756R
英文名称 MPP6
中文名称 棕榈酰化膜蛋白6抗体
别    名 MAGUK p55 subfamily member 6 VELI associated MAGUK 1; MAGUK protein p55T; MPP6; Palmitoylated 6 MAGUK p55 subfamily member 6; PALS2; Protein associated with Lin7 2; VELI associated MAGUK 1; MPP6_HUMAN.  
研究领域 肿瘤  细胞生物  免疫学  染色质和核信号  细胞周期蛋白  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Cow,Horse,Rabbit,Sheep)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 61kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VAM1/MPP6: 431-540/540 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Progression of cells from interphase to mitosis involves alterations in cell structures and activities. The transition from G2 to M phase is induced by M phase promoting factor, or MPF. In M phase, many proteins are phosphorylated directly by MPF or indirectly by kinases activated by MPF. These M phase phosphoproteins (MPPs, or MPHOSPHs) permit disassembly of interphase structures and generation of M phase enzymatic activities and structures. VAM1 or MPP6 is thought to be a nucleolus specific exosome co factor, required for its role in the maturation of 5.8S rRNA.

Subunit:
Interacts with CADM1 (By similarity). Interacts with the LIN7 proteins.

Subcellular Location:
Membrane; Peripheral membrane protein (By similarity).

Tissue Specificity:
Abundant in testis, brain, and kidney with lower levels detectable in other tissues.

Similarity:
Belongs to the MAGUK family.
Contains 1 guanylate kinase-like domain.
Contains 2 L27 domains.
Contains 1 PDZ (DHR) domain.
Contains 1 SH3 domain.

SWISS:
Q9NZW5

Gene ID:
51678

Database links:

Entrez Gene: 51678 Human

Entrez Gene: 56524 Mouse

Entrez Gene: 362359 Rat

Omim: 606959 Human

SwissProt: Q9NZW5 Human

SwissProt: Q9JLB0 Mouse

Unigene: 533355 Human



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