| 产品编号 | bs-5846R |
| 英文名称 | ADAM11 |
| 中文名称 | 去整合素样金属蛋白酶11抗体 |
| 别 名 | A disintegrin and metalloproteinase domain 11; ADA11_HUMAN; MDC; Metalloproteinase like, disintegrin like, and cysteine rich protein. |
| 研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 信号转导 细胞骨架 细胞外基质 泛素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human,Mouse (predicted: Rat,Cow,Sheep) |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 60kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ADAM11: 351-450/769 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq, Jul 2008]. Function: Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Subunit: Can bind to LGI1 and LGI4. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed predominantly in brain. Slightly detected or not at all in other tissues. Post-translational modifications: The precursor is cleaved by a furin endopeptidase. Similarity: Contains 1 disintegrin domain. Contains 1 EGF-like domain. Contains 1 peptidase M12B domain. SWISS: O75078 Gene ID: 4185 Database links: Entrez Gene: 4185 Human Omim: 155120 Human SwissProt: O75078 Human Unigene: 6088 Human 细胞外基质蛋白 |
| 产品图片 |
Sample: A549 Cell (Human) Lysate at 40 ug
Primary: Anti-ADAM11 (bs-5846R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 60 kD 
Sample:
brain (Mouse) Lysate at 40 ug Primary: Anti-ADAM11 (bs-5846R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 60 kD |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
