产品编号 | bs-6077R |
英文名称 | NIT1 |
中文名称 | 腈水解酶1抗体 |
别 名 | NIT1; NIT1_HUMAN; Nitrilase 1; Nitrilase homolog 1. |
研究领域 | 肿瘤 细胞生物 染色质和核信号 神经生物学 信号转导 细胞凋亡 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Human,Mouse,Rat,Dog,Horse,Rabbit) |
产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 36kDa |
细胞定位 | 细胞浆 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NBL1: 111-210/327 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
Play a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. it is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2. Function: Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2 (By similarity). Subcellular Location: Cytoplasm. Mitochondrion. Tissue Specificity: Detected in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. Similarity: Belongs to the UPF0012 family. Contains 1 CN hydrolase domain. SWISS: Q86X76 Gene ID: 4817 Database links: Entrez Gene: 4817 Human Entrez Gene: 27045 Mouse Omim: 604618 Human SwissProt: Q86X76 Human SwissProt: Q8VDK1 Mouse Unigene: 146406 Human Unigene: 12915 Mouse Unigene: 270139 Mouse Unigene: 440362 Mouse Unigene: 64425 Rat |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |