| 产品编号 | bs-2940R |
| 英文名称 | FUCA1 Rabbit pAb |
| 中文名称 | α-L岩藻糖苷酶抗体 |
| 别 名 | alpha L fucosidase I; alpha L fucoside fucohydrolase; alpha-L-fucosidase 1; alpha-L-fucosidase I; alpha-L-fucoside fucohydrolase 1; FUCA; FUCA1; FUCO_HUMAN; Tissue alpha L fucosidase; Tissue alpha-L-fucosidase. |
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Specific References (1) | bs-2940R has been referenced in 1 publications.
[IF=6.22] Gustafson, Callie M., et al. "Age-and sex-specific differences in blood-borne microvesicles from apparently healthy humans." Biology of Sex Differences 6.1 (2015): 1-10. Human.
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| 研究领域 | 肿瘤 细胞生物 免疫学 信号转导 肿瘤细胞生物标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse (predicted: Human,Rat,Pig,Cow,Dog,Horse) |
| 产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 50 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FUCA1/Alpha L fucosidase I: 321-420/466 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Alpha-L-fucosidase,AFU is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Function: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Subunit: Homotetramer. Subcellular Location: Lysosome. DISEASE: Fucosidosis (FUCA1D) [MIM:230000]: An autosomal recessive lysosomal storage disease characterized by accumulation of fucose-containing glycolipids and glycoproteins in various tissues. Clinical signs include facial dysmorphism, dysostosis multiplex, moderate hepatomegaly, severe intellectual deficit, deafness, and according to age, angiokeratomas. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the glycosyl hydrolase 29 family. SWISS: P04066 Gene ID: 2517 Database links: Entrez Gene: 2517 Human Entrez Gene: 71665 Mouse Omim: 612280 Human SwissProt: P04066 Human SwissProt: Q99LJ1 Mouse Unigene: 370858 Human Unigene: 439940 Mouse Unigene: 3469 Rat α-L-岩藻糖苷酶是一种催化含岩藻糖基的糖蛋白、糖脂等生物活性大分子水解酶的溶酶体酸性水解酶。其广泛分布于人体组织细胞、血液和体液中。参与体内糖蛋白、糖脂和寡糖的代谢。由于肝癌患者α-L-岩藻糖苷酶明显升高，目前它被认为是原发性肝癌的一种新的肿瘤标记物。α-L岩藻糖苷酶升高：见于原发性肝癌、转移性肝癌、肝硬化、急性肝炎等。 |
| 产品图片 |
Sample:
Lane 1: Mouse Liver tissue lysates
Lane 2: Mouse NIH/3T3 cell lysates
Primary: Anti-FUCA1 (bs-2940R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 50 kDa
Observed band size: 50 kDa
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
