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Rabbit Anti-ROR beta  antibody (bs-6216R)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-6216R
英文名称 ROR beta
中文名称 维甲酸相关孤儿受体β抗体
别    名 bA133M9.1; NR1F2; Nuclear receptor ROR-beta; Nuclear receptor RZR beta; Nuclear receptor RZR-beta; Nuclear receptor subfamily 1 group F member 2; OTTHUMP00000021486; RAR related orphan receptor B; RAR related orphan receptor beta; Retinoic acid binding receptor beta; Retinoid-related orphan receptor-beta; ROR BETA; Rorb; RORB_HUMAN; RZR BETA; RZRB.   
研究领域 肿瘤  细胞生物  染色质和核信号  神经生物学  信号转导  细胞周期蛋白  细胞分化  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,Rat (predicted: Human,Dog,Cow,Horse,Sheep)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 53kDa
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RORB: 385-470/470 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 ROR beta is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation.

Function:
Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter (By similarity).

Subcellular Location:
Nucleus (Probable).

Similarity:
Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.

SWISS:
Q92753

Gene ID:
6096

Database links:

Entrez Gene: 6096 Human

Entrez Gene: 225998 Mouse

Entrez Gene: 309288 Rat

Omim: 601972 Human

SwissProt: Q92753 Human

SwissProt: Q8R1B8 Mouse

SwissProt: P45446 Rat

Unigene: 494178 Human

Unigene: 234641 Mouse

Unigene: 210157 Rat

Unigene: 231652 Rat



产品图片
Sample:
cerebum (Mouse) Lysate at 40 ug
Primary: Anti- ROR beta (bs-6216R)at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kD
Observed band size: 53 kD
Sample:
Eye(Mouse) Lysate at 40 ug
Eye(Rat) Lysate at 40 ug
Cerebellum(Mouse) Lysate at 40 ug
Cerebellum(Rat) Lysate at 40 ug
Uterus(Mouse) Lysate at 40 ug
Primary: Anti-ROR beta (bs-6216R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kD
Observed band size: 53 kD
Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ROR beta) Polyclonal Antibody, Unconjugated (bs-6216R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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