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Rabbit Anti-HOXB2  antibody (bs-6538R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-6538R
英文名称 HOXB2
中文名称 同源盒蛋白B2抗体
别    名 homeo box 2H; homeo box B2; homeobox B2; Homeobox protein Hox-2.8; Homeobox protein Hox-2H; Homeobox protein Hox-B2; Hox 2 8; Hox 2H; HOX2; HOX2H; HXB2_HUMAN; K8; K8 home protein.  
研究领域 肿瘤  细胞生物  染色质和核信号  转录调节因子  肿瘤细胞生物标志物  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat (predicted: Human,Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit)
产品应用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 39kDa
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HOXB2: 65-160/356 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Function:
Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.

Subunit:
Part of the nuclear protein complex gamma-globin promoter and enhancer binding factor (gamma-PE) composed at least by SATB1 and HOXB2.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Antp homeobox family. Proboscipedia subfamily.
Contains 1 homeobox DNA-binding domain.

SWISS:
P14652

Gene ID:
3212

Database links:

Entrez Gene: 3212 Human

Entrez Gene: 103889 Mouse

Entrez Gene: 100361765 Rat

Omim: 142967 Human

SwissProt: P14652 Human

SwissProt: P0C1T1 Mouse

Unigene: 514289 Human

Unigene: 281153 Mouse



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