| 产品编号 | bs-7011R |
| 英文名称 | SDCCAG8 |
| 中文名称 | 结肠癌抗原8抗体 |
| 别 名 | Antigen NY CO 8; CCCAP; Centrosomal colon cancer autoantigen protein; HSPC085; NPHP10 gene; NY-CO-8; Serologically defined colon cancer antigen 8; Serologically defined colon cancer antigen 8 homolog; SLSN7 gene; SDCG8_HUMAN. |
| 研究领域 | 肿瘤 细胞生物 信号转导 细胞类型标志物 肿瘤细胞生物标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Pig,Cow,Horse,Sheep) |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 83 kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SDCCAG8: 321-420/713 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The exact function of SDCCAG8 remains unknown. It is expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors. Function: Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). May play a role in ciliogenesis. Subunit: Homodimer (By similarity). Interacts with OFD1; the interaction is direct. Interacts with FAM161A. Subcellular Location: Isoform 2: Cytoplasm. Tissue Specificity: Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors. DISEASE: Defects in SDCCAG8 are the cause of Senior-Loken syndrome type 7 (SLSN7) [MIM:613615]. SLSN7 is a renal-retinal disorder characterized by progressive wasting of the filtering unit of the kidney (nephronophthisis), with or without medullary cystic renal disease, and progressive eye disease. Typically this disorder becomes apparent during the first year of life. SWISS: Q86SQ7 Gene ID: 10806 Database links: Entrez Gene: 10806 Human Entrez Gene: 76816 Mouse Omim: 613524 Human SwissProt: Q86SQ7 Human SwissProt: Q80UF4 Mouse Unigene: 591530 Human Unigene: 171399 Mouse Unigene: 205402 Rat |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
