| 产品编号 | bs-4684R |
| 英文名称 | Mammaglobin A Rabbit pAb |
| 中文名称 | 乳腺珠蛋白1抗体 |
| 别 名 | Mammaglobin 1; Mammaglobin A; Mammaglobin-1; Mammaglobin-A; MGB 1; MGB1; Prostatein C3 subunit; prostatein peptide C3; Prostatic steroid binding protein, allele C3(1); SCGB2A2; Secretoglobin; Secretoglobin Family 2A Member 2; SG2A2; UGB 2; UGB2; Uteroglobin; Psbpc3. 乳房珠蛋白1 |
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Specific References (1) | bs-4684R has been referenced in 1 publications.
[IF=3.743] Ying Liu. et al. 1H-NMR based metabolic study of MMTV-PyMT mice along with pathological progress to screen biomarkers for early diagnosis of breast cancer. Mol Omics. 2021 Dec;: IHC ; Mouse.
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| 研究领域 | 肿瘤 细胞生物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | (predicted: Rat) |
| 产品应用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 8.4 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞外基质 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse Mammaglobin A: 41-96/96 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement. Tissue Specificity: Mammary gland specific. Over-expressed in breast cancer. Similarity: Belongs to the secretoglobin family. Lipophilin subfamily. Database links: Entrez Gene: 4250 Human Entrez Gene: 100040203 Mouse Omim: 605562 Human SwissProt: Q13296 Human Unigene: 46452 Human 乳腺球蛋白是一个乳腺相关糖蛋白，它是一个分泌素家族（包括子宫球蛋白和lipophilin）成员的远亲。与其他分泌素家族成员不同，乳腺球蛋白的mRNA在乳腺组织中特异表达。在石蜡组织切片的检测中，该抗体检测乳腺癌组织中的乳腺珠蛋白敏感度高达80%。当和其他乳腺特异标记如GCDFP-15联合应用时，检测乳腺珠蛋白敏感度高达84%。有资料表明检测乳腺球蛋白，在鉴定原发癌是否发生转移中起到至关重要的作用。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
