| 产品编号 | bs-1236R |
| 英文名称 | Involucrin Rabbit pAb |
| 中文名称 | 囊包蛋白/内披蛋白抗体 |
| 别 名 | INVO_HUMAN; involucrin; ivl. |
| 研究领域 | 细胞生物 信号转导 细胞周期蛋白 细胞骨架 细胞外基质 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | (predicted: Human) |
| 产品应用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 64 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Involucrin: 65-180/585 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008]. Function: Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. Subunit: Directly or indirectly cross-linked to cornifelin (CNFN). Subcellular Location: Cytoplasm. Tissue Specificity: Keratinocytes of epidermis and other stratified squamous epithelia. Post-translational modifications: Substrate of transglutaminase. Some glutamines and lysines are cross-linked to other involucrin molecules, to other proteins such as keratin, desmoplakin, periplakin and envoplakin, and to lipids like omega-hydroxyceramide. Similarity: Belongs to the involucrin family. SWISS: P07476 Gene ID: 3713 Database links: Entrez Gene: 3713 Human Entrez Gene: 16447 Mouse Omim: 147360 Human SwissProt: P07476 Human SwissProt: P48997 Mouse Unigene: 516439 Human Unigene: 207365 Mouse Unigene: 142591 Rat 套膜蛋白又称内披蛋白或囊包蛋白，与毛透明蛋白共同构成角质细胞包膜支架的蛋白质。在角质细胞分化时，首先出现在表皮棘层的上层细胞中的标志性蛋白质，该蛋白在角质细胞和其他复层扁平上皮合成的蛋白。最初存在于细胞质中，然后通过转谷氨酰胺酶的作用，转变为交联的膜蛋白。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
