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Goat Anti-Human IgM / HRP antibody (bs-0345G-HRP)
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说明书: 100ul  1ml  
100ul/240.00元
1ml/1580.00元
大包装/询价
产品编号 bs-0345G-HRP
英文名称 Goat Anti-Human IgM / HRP
中文名称 辣根过氧化物酶标记的羊抗人IgM
别    名 Goat Anti-Human IgM (HRP); Immunoglobulin M;   羊抗人-IgM;
Specific References  (3)     |     bs-0345G-HRP has been referenced in 3 publications.
[IF=5.085] Ling Ni. et al. Impaired Cellular Immunity to SARS-CoV-2 in Severe COVID-19 Patients. Front Immunol. 2021; 12: 603563  ELISA ;  Human.  
[IF=22.553] Ni L et al. Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals. Immunity 2020 06 16;526(6)  ELISA ;  Human.  
[IF=2.3] Tian, Lifang, et al. "Autoimmune and inflammatory responses in Kashin?CBeck disease compared with rheumatoid arthritis and osteoarthritis."Human Immunology 72.10 (2011): 812-816..  ELISA ;  Human.  
抗体来源 Goat
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 WB=1:1000-10000 ELISA=1:1000-10000 IHC-P=1:100-1000 IHC-F=1:100-1000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性    状 Liquid
浓    度 2.0 mg/ml
免 疫 原 Native Human IgM 
亚    型 IgG
纯化方法 affinity purified by Protein G
缓 冲 液 10 mM TBS (pH=7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol.
保存条件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.

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