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Rabbit Anti-ZHX2  antibody (bs-7581R)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-7581R
英文名称 ZHX2
中文名称 甲胎蛋白调节蛋白1抗体
别    名 AFP regulator 1; AFR1; Alpha fetoprotein regulator 1; RAF; Regulator of AFP; Zinc finger and homeodomain protein 2; zinc fingers and homeoboxes 2; ZHX2_HUMAN.  
研究领域 细胞生物  免疫学  信号转导  转录调节因子  锌指蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat (predicted: Human,Mouse,Chicken,Dog,Pig,Cow,Horse)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 92kDa
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZHX2: 451-550/837 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008].[FUNCTION] Acts as a transcriptional repressor.[SUBUNIT] Forms homodimers. Also forms heterodimers with ZHX1 and ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts with NFYA.[SUBCELLULAR LOCATION] Nucleus. [TISSUE SPECIFICITY] Ubiquitously expressed. [SIMILARITY] Belongs to the ZHX family.

Function:
Acts as a transcriptional repressor.

Subunit:
Forms homodimers. Also forms heterodimers with ZHX1 and ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts with NFYA.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Belongs to the ZHX family.
Contains 2 C2H2-type zinc fingers.
Contains 4 homeobox DNA-binding domains.

SWISS:
Q9Y6X8

Gene ID:
22882

Database links:
 

UniProtKB/Swiss-Prot: Q9Y6X8.1

Entrez Gene: 22882 Human

Omim: 609185 Human

SwissProt: Q9Y6X8 Human

Unigene: 377090 Human

Unigene: 658443 Human

 



产品图片
Paraformaldehyde-fixed, paraffin embedded (Rat breast); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ZHX2) Polyclonal Antibody, Unconjugated (bs-7581R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Rat thyroid); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ZHX2) Polyclonal Antibody, Unconjugated (bs-7581R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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