| 产品编号 | bs-6856R |
| 英文名称 | NLRP10 |
| 中文名称 | 富含亮氨酸重复结构域蛋白10抗体 |
| 别 名 | CLR11.1; NACHT, leucine rich repeat and PYD containing 10; NACHT, LRR and PYD domains containing protein 10; NACHT, LRR and PYD domains-containing protein 10; NAL10_HUMAN; NALP10; NLR family, pyrin domain containing 10; Nlrp10; NOD8; Nucleotide-binding oligomerization domain protein 8; Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10; PAN5; PYNOD. |
| 研究领域 | 细胞生物 细胞凋亡 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human) |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 75kDa |
| 细胞定位 | 细胞浆 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NLRP10: 401-500/655 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Inhibits CASP1/caspase-1-dependent IL1B secretion and PYCARD-mediated apoptosis, but not that induced by FAS or BID.
Tissue specificity: Widely expressed with highest levels in heart, brain and skeletal muscle. Function: Inhibits CASP1/caspase-1-dependent IL1B secretion and PYCARD-mediated apoptosis, but not that induced by FAS or BID. Subcellular Location: Oligomerizes. Interacts with PYCARD, CASP1 and IL1B. Tissue Specificity: Widely expressed with highest levels in heart, brain and skeletal muscle. Similarity: Belongs to the NLRP family. Contains 1 DAPIN domain. Contains 1 NACHT domain. SWISS: Q86W26 Gene ID: 338322 Database links: Entrez Gene: 338322 Human Entrez Gene: 244202 Mouse Omim: 609662 Human SwissProt: Q86W26 Human SwissProt: Q8CCN1 Mouse Unigene: 449636 Human Unigene: 37991 Mouse |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
