| 产品编号 | bs-7672R |
| 英文名称 | NRH2 |
| 中文名称 | 死亡结构域蛋白NRH2抗体 |
| 别 名 | NRADD; PLAIDD; NRADD_RAT; Death domain-containing membrane protein NRADD; Neurotrophin receptor homolog-2; Neurotrophin receptor-alike death domain protein; P75-like apoptosis-inducing death domain protein. 神经营养因子受体相似的死亡结构域蛋白; |
| 研究领域 | 细胞生物 细胞凋亡 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Mouse,Rat,Dog,Pig,Horse,Sheep) |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 24kDa |
| 细胞定位 | 细胞核 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from rat NRH2: 51-150/228 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
A single transmembrane protein highly expressed in embryonic tissues and involved in inducing apoptosis. Function: Modulates NTRK1 signaling. Can activate severalintracellular signaling pathways, leading to activation of JUN.Promotes translocation of SORT1 to the cell membrane, and therebyhinders lysosomal degradation of SOTR1 and promotes its interactionwith NGFR (By similarity). Both isoform 1 and isoform 2 promoteapoptosis. Subunit: Interacts with NTRK1. Isoform 1 andisoform 2 interact with NGFR. Interacts with SORT1. Subcellular Location: Cell membrane; Single-pass type III membraneprotein. Nucleus (By similarity). Note=Proteolytic processing givesrise to an intracellular domain that translocates to the nucleus. Tissue Specificity: Detected in embryo, including embryonic brain.Detected at very low levels in adult testis, spleen, thymus andlung. Post-translational modifications: Isoform 1 is N-glycosylated. Isoform 2 is not N-glycosylated. Similarity: Contains 1 death domain. SWISS: Q8K5A9 Gene ID: 246143 Database links:
|
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
