产品编号 | bs-7810R |
英文名称 | MFAP1 Rabbit pAb |
中文名称 | 微原纤维胶原相关蛋白1抗体 |
别 名 | MFAP1 is an extracellular protein associated with elastic fiber microfibrils. |
研究领域 | 细胞生物 信号转导 细胞周期蛋白 细胞骨架 细胞外基质 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human,Mouse (predicted: Rat,Pig,Cow,Chicken) |
产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 52 kDa |
检测分子量 | |
细胞定位 | 细胞外基质 分泌型蛋白 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MFAP1: 31-120/439 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
Microfibrils are an important component of the extracellular matrix of many tissues and can either associate with or without elastin. Several microfibril associated proteins (MFAPs) have been cloned, including MFAP1, MFAP3 and MFAP4. The MFAP1 and MFAP3 genes are localized near the fibrillin genes FBN1 and FBN2, respectively. Mutations in FBN1 are linked to Marfan syndrome. Mutations in FBN2 have been linked to congenital contractural arachnodactyly. This suggests roles for MFAP1 and MFAP3 in heritable diseases affecting microfibrils. Deletion of MFAP4 was found in 30 of 31 patients with Smith-Magenis syndrome (SMS), a clinically recognizable multiple congenital anomaly/mental retardation syndrome. Function: Component of the elastin-associated microfibrils. Subcellular Location: Secreted, extracellular space, extracellular matrix. Similarity: Belongs to the MFAP1 family. SWISS: P55081 Gene ID: 4236 Database links: Entrez Gene: 4236 Human Entrez Gene: 100034361 Mouse Entrez Gene: 67532 Mouse Omim: 600215 Human SwissProt: 5EA98 Cow SwissProt: P55081 Human SwissProt: Q9CQU1 Mouse Unigene: 61418 Human Unigene: 270393 Mouse Unigene: 440764 Mouse |
产品图片 | |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |