| 产品编号 | bs-7949R |
| 英文名称 | AOC1 |
| 中文名称 | 阿米洛利结合蛋白1抗体 |
| 别 名 | ABP; Abp1; ABP1_HUMAN; Amiloride binding protein 1 (amine oxidase (copper containing)); Amiloride binding protein 1; Amiloride binding protein; Amiloride sensitive amine oxidase; Amiloride-binding protein; Amiloride-sensitive amine oxidase [copper-containing]; DAO; DAO1; Diamine oxidase; Histaminase; KAO; Kidney amine oxidase. |
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Specific References (1) | bs-7949R has been referenced in 1 publications.
[IF=10.754] Apolloni S et al. Histaminergic transmission slows progression of amyotrophic lateral sclerosis. J Cachexia Sarcopenia Muscle. 2019 Apr 24. WB&ICF ; Mouse.
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| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse (predicted: Human,Rat,Dog,Cow,Horse,Rabbit,Sheep) |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 83kDa |
| 细胞定位 | 细胞外基质 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human AOC1: 601-689/751 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. Function: Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. Subunit: Homodimer; disulfide-linked. Subcellular Location: Secreted, extracellular space. Tissue Specificity: Placenta and kidney. Post-translational modifications: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. Similarity: Belongs to the copper/topaquinone oxidase family. SWISS: P19801 Gene ID: 26 Database links: Entrez Gene: 26 Human Omim: 104610 Human SwissProt: P19801 Human Unigene: 647097 Human |
| 产品图片 |
Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DAO1) Polyclonal Antibody, Unconjugated (bs-7949R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
