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Rabbit Anti-AOC1 antibody (bs-7949R)
~~~促销,代码SSY221101~~~
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说明书: 50ul  100ul  200ul
50ul/1138.00元
100ul/1880.00元
200ul/2900.00元
大包装/询价

产品编号 bs-7949R
英文名称 AOC1
中文名称 阿米洛利结合蛋白1抗体
别    名 ABP; Abp1; ABP1_HUMAN; Amiloride binding protein 1 (amine oxidase (copper containing)); Amiloride binding protein 1; Amiloride binding protein; Amiloride sensitive amine oxidase; Amiloride-binding protein; Amiloride-sensitive amine oxidase [copper-containing]; DAO; DAO1; Diamine oxidase; Histaminase; KAO; Kidney amine oxidase.  
Specific References  (1)     |     bs-7949R has been referenced in 1 publications.
[IF=10.754] Apolloni S et al. Histaminergic transmission slows progression of amyotrophic lateral sclerosis. J Cachexia Sarcopenia Muscle. 2019 Apr 24.  WB&ICF ;  Mouse.  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
产品应用 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 83kDa
细胞定位 细胞外基质 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AOC1: 601-689/751 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.

Function:
Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted, extracellular space.

Tissue Specificity:
Placenta and kidney.

Post-translational modifications:
Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

Similarity:
Belongs to the copper/topaquinone oxidase family.

SWISS:
P19801

Gene ID:
26

Database links:

Entrez Gene: 26 Human

Omim: 104610 Human

SwissProt: P19801 Human

Unigene: 647097 Human



产品图片
Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DAO1) Polyclonal Antibody, Unconjugated (bs-7949R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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