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Rabbit Anti-ZnT-1  antibody (bs-6440R)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-6440R
英文名称 ZnT-1
中文名称 锌转运蛋白1抗体
别    名 SLC30 A1; SLC30A 1; SLC30A1; Solute carrier family 30 (zinc transporter), member 1; Solute carrier family 30 (zinc transporter), member1; Solute carrier family 30 member 1; Solute carrier family 30, member 1; Zinc transporter 1; Zinc transporter1; ZNT 1; ZnT-1; ZNT1_HUMAN; ZRC 1; ZRC1.  
Specific References  (1)     |     bs-6440R has been referenced in 1 publications.
[IF=6.543] Xiao Chuanpi. et al. High Temperature-Induced Oxidative Stress Affects Systemic Zinc Homeostasis in Broilers by Regulating Zinc Transporters and Metallothionein in the Liver and Jejunum. Oxid Med Cell Longev. 2022;2022:1427335  WB ;  Broiler Chicks.  
研究领域 细胞生物  免疫学  发育生物学  神经生物学  转录调节因子  转运蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,Mouse,Rat (predicted: Dog,Pig,Cow,Horse)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 55kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZnT-1: 131-330/507 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT-1, a ubiquitous protein, localizes to the plasma membrane to aid in the export of zinc out of cells.

Function:
May be involved in zinc transport out of the cell.

Subunit:
Multimer.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.

SWISS:
Q9Y6M5

Gene ID:
7779

Database links:

Entrez Gene: 7779 Human

Entrez Gene: 22782 Mouse

Entrez Gene: 58976 Rat

Omim: 609521 Human

SwissProt: Q9Y6M5 Human

SwissProt: Q60738 Mouse

SwissProt: Q62720 Rat

Unigene: 519469 Human

Unigene: 9024 Mouse

Unigene: 10120 Rat



产品图片
Sample:Large intestine (mouse) Lysate at 40 ug
Primary: Anti- ZnT-1(bs-6440R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55kD
Observed band size: 55kD
Sample:Lovo cell (human) Lysate at 40 ug
Primary: Anti- ZnT-1(bs-6440R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55kD
Observed band size: 55kD
Sample:
Lane 1: Mouse Small intestine tissue lysates
Lane 2: Mouse Heart tissue lysates
Lane 3: Rat Small intestine tissue lysates
Lane 4: Rat Heart tissue lysates
Lane 5: Human HeLa cell lysates
Lane 6: Human U251 cell lysates
Lane 7: Human K562 cell lysates
Lane 8: Human HepG2 cell lysates
Primary: Anti-ZnT-1 (bs-6440R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kDa
Observed band size: 50 kDa
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