| 产品编号 | bs-9731R |
| 英文名称 | EML3 |
| 中文名称 | 微管相关蛋白样蛋白3抗体 |
| 别 名 | Echinoderm microtubule associated protein like 3; ELP 95; EMAP 3; EMAP3; EMAP-3; EML 3; EML3; EML-3; FLJ 35827; MGC 111422; EMAL3_HUMAN. |
| 研究领域 | 细胞生物 细胞周期蛋白 细胞分化 细胞骨架 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Rabbit) |
| 产品应用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 95kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EML3: 451-550/896 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
At the onset of mitosis, assembly of the mitotic spindle requires a global change in the activity of microtubule-binding proteins. EML3 (Echinoderm microtubule-associated protein-like 3) is a 896 amino acid protein that likely modifies microtubule dynamics by making them longer. Through colocalization with spindle microtubules during mitosis, EML3 plays a role in correct metaphase chromosome alignment. EML3 contains a nuclear localization signal and a microtubule-binding domain. The gene encoding EML3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. Function: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity). Subcellular Location: Cytoplasmic Similarity: Belongs to the WD repeat EMAP family. Contains 9 WD repeats. SWISS: Q32P44 Gene ID: 256364 Database links: Entrez Gene: 256364 Human Entrez Gene: 225898 Mouse SwissProt: Q32P44 Human SwissProt: Q8VC03 Mouse |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
