| 产品编号 | bs-9903R |
| 英文名称 | SCUBE1 |
| 中文名称 | 新型血小板相关血管内皮分泌蛋白SCUBE1抗体 |
| 别 名 | SCUB1_HUMAN; SCUBE 1; SCUBE1; Signal peptide, CUB and EGF-like domain-containing protein 1. |
| 研究领域 | 心血管 内皮细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:50-200, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 105kDa |
| 细胞定位 | 细胞膜 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SCUBE1: 451-550/988 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology. Function: Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology. Subunit: Forms homooligomers and heterooligomers with SCUBE2 and SCUBE3. Subcellular Location: Secreted. Cell membrane. Tissue Specificity: Detected in endothelial cells. Highly expressed in platelets. Stored in platelet alpha granules, and transferrred to the cell surface upon activation and aggregation. A smaller form, probably produced by limited proteolysis, after being released from the storage granules, is associated with thrombus and localized with the subendothelial matrices in atherosclerotic plaques. Post-translational modifications: N-glycosylated. Could be proteolytically cleaved to release a smaller active fragment. Similarity: Contains 1 CUB domain. Contains 9 EGF-like domains. SWISS: Q8IWY4 Gene ID: 80274 Database links: Entrez Gene: 80274 Human Entrez Gene: 64706 Mouse Omim: 611746 Human SwissProt: Q8IWY4 Human SwissProt: Q6NZL8 Mouse Unigene: 133995 Human Unigene: 40393 Mouse |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
