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Rabbit Anti-CK15 antibody (bs-4762R)
~~~促销,代码SSY221101~~~
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说明书: 50ul  100ul  200ul
50ul/1138.00元
100ul/1880.00元
200ul/2900.00元
大包装/询价

产品编号 bs-4762R
英文名称 CK15
中文名称 细胞角蛋白15抗体
别    名 K1C15_HUMAN; Cytokeratin 15; CK 15; CK15; Cytokeratin15; K15; K1CO; Keratin 15; Keratin 15 basic; Keratin 15 beta; Keratin complex 1 acidic gene 15; Keratin type I cytoskeletal 15; Keratin15; KRT 15; KRTB; KRTL15; keratin-15, basic; Type I cytoskeletal 15.  
Specific References  (2)     |     bs-4762R has been referenced in 2 publications.
[IF=1.92] Li et al. miR‑339‑5p negatively regulates loureirin A‑induced hair follicle stem cell differentiation by targeting DLX5. (2018) Mol.Med.Rep. 18:1279-1286  ICC ;  Rat.  
[IF=1.329] Ziwei Luo. et al. miR‐203a‐3p promotes loureirin A‐induced hair follicle stem cells differentiation by targeting Smad1. Anat Rec. 2021 Mar;304(3):531-540  IF ;  Rat.  
研究领域 细胞生物  免疫学  信号转导  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 49kDa
细胞定位 细胞核 细胞浆 细胞外基质 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CK15: 351-456/456 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. [provided by RefSeq, Jul 2008].

Subunit:
Heterotetramer of two type I and two type II keratins.

Tissue Specificity:
Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate.

Similarity:
Belongs to the intermediate filament family.

SWISS:
P19012

Gene ID:
3866

Database links:

Entrez Gene: 3866 Human

Entrez Gene: 16665 Mouse

Entrez Gene: 287700 Rat

Omim: 148030 Human

SwissProt: P19012 Human

SwissProt: Q61414 Mouse

SwissProt: Q6IFV3 Rat

Unigene: 654570 Human

Unigene: 440010 Mouse

Unigene: 153568 Rat



产品图片
Sample:
Lung (Mouse) Lysate at 40 ug
Primary: Anti- CK15 (bs-4762R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 49 kD
Observed band size: 49 kD
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