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产品中心-北京博奥森生物技术有限公司
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Rabbit Anti-C1GALT1  antibody (bs-9685R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-9685R
英文名称 C1GALT1
中文名称 N-乙酰半乳糖胺糖蛋白3、β-半乳糖转移酶1抗体
别    名 B3Gal T8; Beta 1 3 galactosyltransferase; C1GALT; Core 1 beta1 3 galactosyltransferase 1; Core 1 beta3 Gal T; Core 1 O glycan T synthase; Core 1 synthase glycoprotein N acetylgalactosamine 3 beta galactosyltransferase 1; Core 1 UDP galactose:N acetylgalactosamine alpha R beta 1 3 galactosyltransferase; Glycoprotein N acetylgalactosamine 3 beta galactosyltransferase 1; T synthase.  
研究领域 心血管  细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit)
产品应用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 40kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human C1GALT1: 171-270/363 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 C1GALT1 is a glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is synthesized by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended O-glycans in glycoproteins. C1GALT1 plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.

Function:
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.

Subunit:
Homodimer; disulfide-linked (By similarity). Interacts with the C1GALT1C1 chaperone; required for galactosyltransferase activity.

Subcellular Location:
Membrane.

Tissue Specificity:
Widely expressed. Highly expressed in kidney, heart, placenta and liver.

Similarity:
Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.

SWISS:
Q9NS00

Gene ID:
56913

Database links:

Entrez Gene: 56913 Human

Omim: 610555 Human

SwissProt: Q9NS00 Human



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