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Rabbit Anti-FAM64A  antibody (bs-11005R)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-11005R
英文名称 FAM64A
中文名称 染色体分离调节蛋白1抗体
别    名 FA64A_HUMAN; FAM64A; family with sequence similarity 64, member A; FLJ10156; FLJ10491; Protein FAM64A; RCS1; regulator of chromosome segregation 1; PIMREG; CALM-interactor expressed in thymus and spleen; PICALM-interacting mitotic regulator; Regulator of chromosome segregation protein 1;  
研究领域 细胞生物  免疫学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse (predicted: Human,Rat,Pig,Horse)
产品应用 WB=1:500-2000, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 27kDa
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RCS1/FAM64A: 151-248/248 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 PIMREG (PICALM Interacting Mitotic Regulator) is a Protein Coding gene. Diseases associated with PIMREG include Suppurative Periapical Periodontitis.

Function:
During mitosis, may play a role in the control of metaphase-to-anaphase transition.

Subunit:
Isoform 1 and isoform 2 interact with PICALM; this interaction may target PICALM to the nucleus (PubMed:16491119). During mitosis, associates with HDAC2 and MTA2 subunits of the chromatin-remodeling NuRD complex; this association is strongest at prometaphase and decreases as the cell progresses through metaphase and anaphase (PubMed:18757745).

Subcellular Location:
Nucleus

Tissue Specificity:
Expressed in thymus (at protein level). Detected in spleen, colon, ovary and small intestines.

Post-translational modifications:
Ubiquitinated by the anaphase-promoting complex/cyclosome (APC/C) complex in the presence of FZR1, leading to its degradation by the proteasome during mitotic exit. However, degradation is not essential for normal mitotic progression within a single cell cycle.

SWISS:
Q9BSJ6

Gene ID:
54478

Database links:

Entrez Gene: 54478 Human

SwissProt: Q9BSJ6 Human

Unigene: 592116 Human



产品图片
Sample:
Thymus (Mouse) Lysate at 40 ug
Spleen (Mouse) Lysate at 40 ug
Primary: Anti- FAM64A (bs-11005R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 25 kD
Sample:
Ovary (Mouse) Lysate at 40 ug
Primary: Anti- FAM64A (bs-11005R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 27/26 kD
Sample:
Thymus(Mouse) Lysate at 40 ug
Primary: Anti- FAM64A (bs-11005R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 27/26 kD
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