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Rabbit Anti-APOC3 antibody (bs-4741R)
~~~促销,代码SSY221101~~~
订购热线:400-901-9800
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说明书: 50ul  100ul  200ul
50ul/1138.00元
100ul/1880.00元
200ul/2900.00元
大包装/询价
产品编号 bs-4741R
英文名称 APOC3
中文名称 载脂蛋白C3抗体
别    名 APO C3; Apo CIII; Apo-CIII; APOC 3; ApoC III; ApoC-III; APOC3; APOC3_HUMAN; ApoCIII; Apolipoprotein C III; Apolipoprotein C-III; Apolipoprotein C3; ApolipoproteinCIII; MGC150353.  
Specific References  (4)     |     bs-4741R has been referenced in 4 publications.
[IF=2.984] Yitong Pan. et al. N-acetyl-L-tryptophan attenuates hepatic ischemia-reperfusion injury via regulating TLR4/NLRP3 signaling pathway in rats. Peerj. 2021 Aug;9:e11909  WB,IF ;  Rat.  
[IF=2.136] Hou Z et al. Comparative proteomic identification of capacitation and noncapacitation swamp buffalo spermatozoa. Theriogenology. 2019 Feb 7;128:176-183.  WB ;  buffalo.  
[IF=2.136] Hou Z et al. Comparative proteomic identification buffalo spermatozoa during in vitro capacitation. (2018) Theriogenology 126:303-309.  WB ;  Buffalo.  
[IF=4.87] Lozhkin, Andrey, et al. "NADPH oxidase 4 regulates vascular inflammation in aging and atherosclerosis." Journal of Molecular and Cellular Cardiology (2016).  IHC-F ;  Mouse.  
研究领域 肿瘤  心血管  细胞生物  免疫学  信号转导  脂蛋白  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Cow, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 9kDa
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human APOC3: 21-80/99 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. It inhibits lipoprotein lipase and hepatic lipase and it is thought to delay catabolism of triglyceride-rich particles. An increase in apoC-III levels induces the development of hypertriglyceridemia.

Function:
Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles.

Subcellular Location:
Secreted.

Tissue Specificity:
Constitutes 50% of the protein fraction of VLDL and 2% of that of HDL. Synthesized predominantly in liver and to a lesser degree in intestine.

Post-translational modifications:
O-linked glycan consists of Gal-GalNAc disaccharide, further modified with up to 3 sialic acid residues. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan.

DISEASE:
Hyperalphalipoproteinemia 2 (HALP2) [MIM:614028]: A condition characterized by high levels of high density lipoprotein (HDL) and increased HDL cholesterol levels. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the apolipoprotein C3 family.

SWISS:
P02656

Gene ID:
345

Database links:

Entrez Gene: 345 Human

Entrez Gene: 11814 Mouse

Entrez Gene: 24207 Rat

Omim: 107720 Human

SwissProt: P02656 Human

SwissProt: P33622 Mouse

SwissProt: P06759 Rat

Unigene: 73849 Human

Unigene: 390161 Mouse

Unigene: 195323 Rat



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