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SLC14A2 Rabbit pAb (bs-11801R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-11801R
英文名称 SLC14A2 Rabbit pAb
中文名称 尿素转运型糖蛋白A2抗体
别    名 UT-A; HUT2; kidney; MGC119566; MGC119567; Slc14a2; Solute carrier family 14(urea transporter), member 2; Solute carrier family 14 member 2; Urea transporter 2; Urea transporter; Urea transporter, kidney; UT-A2; UT2; UT2_HUMAN; UTA; UTR; FLJ16167; hUT-A6.  
Specific References  (1)     |     bs-11801R has been referenced in 1 publications.
[IF=2.976] Franziska Jäger. et al. Immunohistochemical detection of urea transporter-A in the tear-producing part of the lacrimal system. ANN ANAT. 2022 Oct;244:151991  IHC ;  Human, Mouse, Pig.  
研究领域 肿瘤  神经生物学  信号转导  通道蛋白  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human,Mouse,Rat)
产品应用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 101 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC14A2/UT-A: 501-600/920 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]

Function:
Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism.

Subunit:
Isoform 1 interacts with SNAPIN which may be important for recruitment to the plasma membrane.

Subcellular Location:
Apical cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Isoform 1 and isoform 2 are expressed in the inner medulla of the kidney.

Similarity:
Belongs to the urea transporter family.

SWISS:
Q15849

Gene ID:
8170

Database links:

Entrez Gene: 8170 Human

Entrez Gene: 27411 Mouse

Entrez Gene: 54302 Rat

Omim: 601611 Human

SwissProt: Q15849 Human

SwissProt: Q8R4T9 Mouse

SwissProt: Q62668 Rat

Unigene: 710927 Human

Unigene: 44158 Mouse

Unigene: 10157 Rat



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