产品编号 | bs-11915R |
英文名称 | NRSN1 Rabbit pAb |
中文名称 | 神经囊泡膜蛋白1抗体 |
别 名 | Neurensin-1; Neuro-p24; NRSN1; NRSN1_HUMAN; p24; Vesicular membrane protein of 24 kDa; Vesicular membrane protein p24; VMP. |
研究领域 | 细胞生物 发育生物学 神经生物学 信号转导 细胞膜蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
克 隆 号 | |
交叉反应 | (predicted: Human,Mouse,Rat,Rabbit,Horse) |
产品应用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 21 kDa |
检测分子量 | |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NRSN1: 101-195/195 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
Neurensin-1 (NRSN1), also designated Vesicular membrane protein of 24 kDa (VMP) or Neuro-p24, is a 195 amino acid multi-pass membrane protein belonging to the VMP family that is involved in the transport of neural organelle transport and in the transduction of nerve signals or in nerve growth. Expressed solely in brain, Neurensin-1 is also thought to play a role in neurite extension. The gene encoding Neurensin-2 maps to human chromosome 6, which contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. Function: May play an important role in neural organelle transport, and in transduction of nerve signals or in nerve growth. May play a role in neurite extension. Subcellular Location: Membrane. Localizes mainly to neurites. Tissue Specificity: Expressed in brain. Not detectable in other tissues tested. Similarity: Belongs to the VMP family. SWISS: Q8IZ57 Gene ID: 140767 Database links: Entrez Gene: 140767 Human Entrez Gene: 22360 Mouse SwissProt: Q8IZ57 Human SwissProt: P97799 Mouse Unigene: 726270 Human Unigene: 4766 Mouse Unigene: 225156 Rat |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |