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PEX5L Rabbit pAb (bs-12096R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-12096R
英文名称 PEX5L Rabbit pAb
中文名称 过氧化物酶体生成蛋白5相关蛋白抗体
别    名 Peroxin 5R; PEX5-related protein; Peroxin 5 related protein; Peroxisome biogenesis factor 5 like; PEX2 related protein; PEX5-like protein; PEX5R; Pex5Rp; PEX5R_HUMAN; PEX2-related protein; Peroxin-5-related protein; Pex5Rp; Peroxisome biogenesis factor 5-like; PXR2; PEX5R; PXR2B; PEX5RP; TRIP8b.  
研究领域 神经生物学  通道蛋白  细胞膜受体  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human,Mouse,Rat)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 70 kDa
检测分子量
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Peroxin 5R: 101-200/626 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Peroxisomes are single-membrane bound organelles present in virtually all eukaryotic cells. They are involved in numerous catabolic and anabolic pathways, including beta-oxidation of very long chain fatty acids, metabolism of hydrogen peroxide, plasmalogen biosynthesis and bile acid synthesis. The Peroxin gene family, which includes more than 20 members, is required for peroxisome biogenesis. Peroxin 5R, also known as PEX5-related protein or Peroxisome biogenesis factor 5-like, is a 626 amino acid protein that is mainly expressed in brain, with some expression in testis and pancreas. Peroxin 5R contains five TPR repeats, which enable protein-protein interactions and assembly of large multiprotein complexes. There are three isoforms of Peroxin 5R that are produced as a result of alternative splicing events. These isoforms bind C-terminal peroxisome-targeting signals in a similar manner to Peroxin-5. Peroxin 5R interacts with Rab 8b, possibly playing a role in vesicular trafficking and neurotransmitter release.

Function:
Belongs to the peroxisomal targeting signal receptor family. Contains 5 TPR repeats.

Subunit:
Interacts with RAB8B (By similarity). May interact with the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type); the relevance of such interaction is however unclear.

Subcellular Location:
Cytoplasm. Membrane; Peripheral membrane protein.

Tissue Specificity:
Mainly expressed in brain. Also expressed in pancreas, testis and pituitary.

Similarity:
Belongs to the peroxisomal targeting signal receptor family.
Contains 5 TPR repeats.

Gene ID:
51555

Database links:
Entrez Gene: 51555 Human

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