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Rabbit Anti-DNER  antibody (bs-12115R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-12115R
英文名称 Rabbit Anti-DNER  antibody
中文名称 脑表皮生长因子跨膜蛋白DNER抗体
别    名 Brain EGF repeat-containing transmembrane protein; Bret; Delta and Notch-like epidermal growth factor-related receptor; Delta/notch-like EGF-related receptor; Dner; DNER_HUMAN; PRO299; Transmembrane protein Bet; UNQ26.  
研究领域 神经生物学  信号转导  干细胞  细胞表面分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog,Cow,Sheep)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 75kDa
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNER: 185-300/737 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.

Function:
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.

Subunit:
Interacts with AP1G1. Interacts with NOTCH1.

Subcellular Location:
Cell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region.

Tissue Specificity:
Expressed in brain, spinal cord and adrenal gland.

Similarity:
Contains 10 EGF-like domains.
Contains 1 follistatin-like domain.

SWISS:
Q8NFT8

Gene ID:
92737

Database links:

Entrez Gene: 92737 Human

Entrez Gene: 227325 Mouse

Entrez Gene: 316573 Rat

Omim: 607299 Human

SwissProt: Q8NFT8 Human

SwissProt: Q8JZM4 Mouse

Unigene: 234074 Human

Unigene: 292560 Mouse



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