| 产品编号 | bs-12309R |
| 英文名称 | Rabbit Anti-Hoxb3 antibody |
| 中文名称 | 同源盒蛋白HoxB3抗体 |
| 别 名 | Homeo box 2G; Homeo box B3; Homeobox B3; Homeobox protein Hox-2.7; Homeobox protein Hox-2G; Homeobox protein Hox-B3; Homeobox protein HoxB3; Hox 2.7; HOX 2G; HOX2; Hox2.7; HOX2G; HOXB3; HXB3_HUMAN. |
| 研究领域 | 细胞生物 发育生物学 干细胞 淋巴细胞 b-淋巴细胞 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) |
| 产品应用 | WB=1:500-2000, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 44kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Hoxb3: 201-300/431 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
HOX genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. There are multiple transcripts of the Hoxb3 gene, and the anterior boundaries of its expression vary at different stages of development. Hoxb3 plays a role in the proliferation and differentiation of both early myeloid and lymphoid developmental pathways. Hoxb3 also has overlapping function in mediating the migration of pharyngeal organ primordia and is expressed in very restricted domains in the future hindbrain. Hoxb6 controls the generation, proliferation and survival of erythroid progenitor cells. The Hoxb6 protein is expressed in the suprabasal layer of the early developing epidermis and throughout the upper layers of late fetal and adult human skin. Hoxb6 is cytoplasmically expressed throughout fetal epidermal development, but displays nuclear expression in normal adult skin. Hoxb6 protein also has nuclear expression in hyperproliferative skin conditions, but appears to be localized in the cytoplasm in basal and squamous cell carcinomas. Hoxb6 genes are also expressed in normal adult lung. Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Subcellular Location: Nucleus. Similarity: Belongs to the Antp homeobox family. Contains 1 homeobox DNA-binding domain. SWISS: P14651 Gene ID: 3213 Database links: Entrez Gene: 3213 Human Entrez Gene: 15410 Mouse Omim: 142966 Human SwissProt: P14651 Human SwissProt: P09026 Mouse |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
