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Rabbit Anti-ACN9  antibody (bs-12444R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-12444R
英文名称 ACN9
中文名称 ACN9蛋白抗体
别    名 ACN 9; acn9; ACN9 homolog (S. cerevisiae); ACN9 homolog; SDHF3_HUMAN; DC11; Protein ACN9 homolog mitochondrial; Protein ACN9 homolog, mitochondrial; Succinate Dehydrogenase Complex Assembly Factor 3; SDH Assembly Factor 3; DC11; Sdh7;  
研究领域 细胞生物  信号转导  转录调节因子  通道蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 11kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ACN9: 21-100/125 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 SDHAF3 (Succinate Dehydrogenase Complex Assembly Factor 3) is a Protein Coding gene. Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

Function:
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

Subcellular Location:
Mitochondrion matrix

Similarity:
Belongs to the ACN9 family.
Belongs to the complex I LYR family. SDHAF3 subfamily.

SWISS:
Q9NRP4

Gene ID:
57001

Database links:

Entrez Gene: 57001 Human

Entrez Gene: 71238 Mouse

SwissProt: Q9NRP4 Human

SwissProt: Q8BQU3 Mouse

Unigene: 592269 Human

Unigene: 389086 Mouse



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