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APMAP Rabbit pAb (bs-12490R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-12490R
英文名称 APMAP Rabbit pAb
中文名称 脂肪细胞膜相关蛋白抗体
别    名 Adipocyte plasma membrane associated protein; Adipocyte plasma membrane-associated protein; apmap; APMAP_HUMAN; BSCv; BSCv protein; C20orf3; Chromosome 20 open reading frame 3; Protein BSCv.  
研究领域 肿瘤  细胞生物  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Horse,Monkey)
产品应用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 46 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human APMAP: 151-250/416 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 APMAP is a 416 amino acid single-pass type II membrane protein that belongs to the strictosidine synthase family and is thought to play a role in adipocyte differentiation. The gene encoding C20orf3 maps to human chromosome 20, which houses over 600 genes some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

Function:
Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in adipocyte differentiation.

Subcellular Location:
Membrane.

Tissue Specificity:
Liver, glomerular and tubular structures of the kidney, endothelial cells, arterial wall and pancreatic islets of Langerhans (at protein level). Found ubiquitously in adult as well as in embryonic tissues. In adult tissue, the highest expression is found in the liver, placenta and heart. Found on the cell surface of monocytes. In embryonic tissue, the highest expression levels is found in the liver and the kidney.

Similarity:
Belongs to the strictosidine synthase family.

SWISS:
Q9HDC9

Gene ID:
57136

Database links:

Entrez Gene: 57136 Human

Entrez Gene: 71881 Mouse

Entrez Gene: 366227 Rat

Omim: 615884 Human

SwissProt: Q3T0E5 Cow

SwissProt: Q9HDC9 Human

SwissProt: Q9D7N9 Mouse

SwissProt: Q7TP48 Rat



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