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FOXF2 Rabbit pAb (bs-13201R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-13201R
英文名称 FOXF2 Rabbit pAb
中文名称 叉头蛋白F2抗体
别    名 FKH L6; FKHL 6; FKHL6; Forkhead box F2; Forkhead box protein F2; Forkhead like 6; Forkhead related activator 2; Forkhead related protein FKHL6; Forkhead related transcription factor 2; FOX F2; FOXF 2; FREAC 2; FREAC2; OTTHUMP00000017863;  
研究领域 肿瘤  细胞生物  发育生物学  神经生物学  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse (predicted: Human,Rat,Chicken)
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 46 kDa
检测分子量
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FOXF2: 65-160/444 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. Development of the vertebrate gut is controlled by paracrine crosstalk between the endodermal epithelium and the associated splanchnic mesoderm. FOXF2 (forkhead box F2), also known as FKHL or FREAC2, is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes. FOXF2 interacts with transcription factors TFIIB and TBP, and may be involved in regulating transcription in embryogenesis and pattern formation in multicellular organisms. FOXF2-deficient mice develop cleft palate and an abnormal tongue, which suggests that FOXF2 may be critical for palatogenesis.

Function:
FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes.

Subunit:
Interacts with the transcription factors TBP and TFIIB.

Subcellular Location:
Nuclear.

Similarity:
Contains 1 fork-head DNA-binding domain.

SWISS:
Q12947

Gene ID:
2295

Database links:

Entrez Gene: 2295 Human

Entrez Gene: 14238 Mouse

Omim: 603250 Human

SwissProt: Q12947 Human

SwissProt: O54743 Mouse

Unigene: 484423 Human

Unigene: 125548 Mouse



产品图片
ample: Lane 1: Mouse Liver tissue lysates Lane 2: Mouse Lung tissue lysates Primary: Anti-FOXF2 (bs-13201R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 46 kDa Observed band size: 46 kDa
Sample: Kidney (Mouse) Lysate at 40 ug Primary: Anti- FOXF2 (bs-13201R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 46 kD Observed band size: 46 kD
Sample: Large intestine (Mouse) Lysate at 40 ug Primary: Anti- FOXF2 (bs-13201R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 46 kD Observed band size: 46 kD
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