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ZBTB5 Rabbit pAb (bs-13581R)  
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产品编号 bs-13581R
英文名称 ZBTB5 Rabbit pAb
中文名称 锌指蛋白ZBTB5抗体
别    名 5930421I10; 9430083K24Rik; AI646847; Expressed in brain and neural tube; KIAA0354; mKIAA0354; OTTMUSP00000007812; OTTMUSP00000007813; OTTMUSP00000007814; RP11-397D12.5; RP23-218A4.2; Transcription factor ZNF POZ; Zbtb5; ZBTB5_HUMAN; Zinc finger and BTB domain containing protein 5; Zinc finger and BTB domain-containing protein 5.  
研究领域 转录调节因子  锌指蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human (predicted: Mouse,Rat,Rabbit,Sheep,Cow,Chicken,Dog,Horse)
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 74 kDa
检测分子量
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZBTB5: 581-677/677 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 5 (ZBTB5) is a 677 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB5 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB5 functions as a transcription regulator.

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 BTB (POZ) domain.
Contains 2 C2H2-type zinc fingers.

SWISS:
O15062

Gene ID:
9925

Database links:

Entrez Gene: 9925 Human

Entrez Gene: 230119 Mouse

Entrez Gene: 298084 Rat

SwissProt: O15062 Human

SwissProt: Q7TQG0 Mouse

Unigene: 161276 Human



产品图片
Sample:MCF-7 (Human)cell Lysate at 40 ug Primary: Anti-ZBTB5(bs-13581R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 74kD Observed band size: 75kD
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