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Rabbit Anti-DCL-1  antibody (bs-13760R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-13760R
英文名称 DCL-1
中文名称 C型凝集素受体CLEC13A抗体
别    名 CD302; CLEC13A; DCL1; C-type lectin domain family 13 member A; C-type lectin BIMLEC; CD302_HUMAN.  
研究领域 肿瘤  细胞生物  细胞粘附分子  细胞表面分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog,Horse,Rabbit)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 26kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DCL-1: 51-150/232 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 DCL-1 is a 232 amino acid single-pass type I membrane protein involved in endocytosis, phagocytosis and cell adhesion and migration. A C-type lectin receptor, DCL-1 is widely expressed with highest levels found in peripheral blood, myeloid and B lymphoid cell lines, liver, ovary and lung. DCL-1 undergoes alternative splicing to produce three isoforms designated DCL-1 isoform 1, isoform 2 (also known as fusion protein variant V34-2) and isoform 3 (also designated fusion protein variant V33-2). DCL-1 isoforms 2 and 3 are produced in malignant lympoma cells, known as Hodgkin and Reed-Sternberg (HRS) cells. DCL-1 contains one C-type lectin domain and is encoded by a gene that maps to human chromosome 2q24.2. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome.

Function:
Expressed in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.

Subcellular Location:
Membrane.

Similarity:
Contains 1 C-type lectin domain.

SWISS:
Q8IX05

Gene ID:
9936

Database links:

Entrez Gene: 9936 Human

Entrez Gene: 66205 Mouse

Entrez Gene: 295629 Rat

Omim: 612246 Human

SwissProt: Q8IX05 Human

SwissProt: Q9DCG2 Mouse

SwissProt: Q5FVR3 Rat

Unigene: 130014 Human

Unigene: 674903 Human

Unigene: 227281 Mouse

Unigene: 98436 Rat



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