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Rabbit Anti-phospho-CEBPE (Thr74)  antibody (bs-13823R)
~~~促销代码KT202410~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-13823R
英文名称 Rabbit Anti-phospho-CEBPE (Thr74)  antibody
中文名称 磷酸化转录调节因子C/EBPε抗体
别    名 CEBPE (phospho T74); p-CEBPE (phospho T74); C/EBP epsilon; CCAAT/enhancer binding protein (C/EBP) epsilon; CCAAT/enhancer binding protein epsilon; CCAAT/enhancer-binding protein epsilon; CEBPE; CEBPE_HUMAN; CRP 1; CRP1.  
产品类型 磷酸化抗体 
研究领域 细胞生物  免疫学  信号转导  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 31kDa
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human CEBPE around the phosphorylation site of Thr74.: PG(p-T)P 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

Function:
C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.

Subcellular Location:
Nucleus.

Tissue Specificity:
Strongest expression occurs in promyelocyte and late-myeloblast-like cell lines.

Post-translational modifications:
Phosphorylated.

SWISS:
Q15744

Gene ID:
1053

Database links:

Entrez Gene: 1053 Human

Entrez Gene: 110794 Mouse

Entrez Gene: 25410 Rat

Omim: 600749 Human

SwissProt: Q15744 Human

SwissProt: Q6PZD9 Mouse

SwissProt: P56261 Rat

Unigene: 558308 Human

Unigene: 236223 Mouse

Unigene: 44462 Rat



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