| 产品编号 | bs-10563R |
| 英文名称 | ARPC1B |
| 中文名称 | 肌动蛋白相关蛋白2/3复合亚单位B1抗体 |
| 别 名 | ARC1B_HUMAN; Actin-related protein 2/3 complex subunit 1B; ARC41; Arp2/3 complex 41 kDa subunit; p41-ARC; actin related protein 2/3 complex subunit 1B; IMD71; PLTEID; p40-ARC; |
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Specific References (1) | bs-10563R has been referenced in 1 publications.
[IF=3.698] Weimin Ni. et al. Actin Related Protein 2/3 Complex Subunit 1 up-regulation in the hypothalamus prevents high-fat diet induced obesity. EUR J NEUROSCI. 2022 Nov;: IF ; Mouse.
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| 研究领域 | 信号转导 细胞骨架 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat) |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 41kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ARPC1B: 101-200/372 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase. [provided by RefSeq, Mar 2011] Function: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Subunit: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Subcellular Location: Cytoplasm, cytoskeleton. Similarity: Belongs to the WD repeat ARPC1 family. Contains 6 WD repeats. SWISS: O15143 Gene ID: 10095 Database links: Entrez Gene: 10095 Human Entrez Gene: 11867 Mouse Omim: 604223 Human SwissProt: O15143 Human SwissProt: Q9WV32 Mouse Unigene: 489284 Human Unigene: 30010 Mouse |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
