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Rabbit Anti-CRYL1  antibody (bs-14079R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-14079R
英文名称 CRYL1
中文名称 晶状体蛋白λ抗体
别    名 CRY; CRYL 1; Crystallin lambda 1; GDH; Gul3DH; L gulonate 3 dehydrogenase; Lambda CRY; Lambda crystallin homolog; MGC149525; MGC149526.  λ-crystallin; λ crystallin.
研究领域 肿瘤  细胞生物  神经生物学  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 35kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CRYL1: 65-170/319 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The uronate cycle functions as an alternative glucose metabolic pathway, accounting for about 5% of daily glucose catabolism. The product of this gene catalyzes the dehydrogenation of L-gulonate into dehydro-L-gulonate in the uronate cycle. The enzyme requires NAD(H) as a coenzyme, and is inhibited by inorganic phosphate. A similar gene in the rabbit is thought to serve a structural role in the lens of the eye. [provided by RefSeq, Jul 2008]

Function:
CRYL1 is involved in the uronate cycle which functions as an alternative glucose metabolic pathway, accounting for about 5% of daily glucose catabolism. CRYL1 catalyzes the dehydrogenation of L-gulonate into dehydro-L-gulonate. The enzyme requires NAD(H) as a coenzyme, and is inhibited by inorganic phosphate.

Subcellular Location:
Cytoplasmic

Tissue Specificity:
Widely expressed, with highest levels in liver and kidney.

Similarity:
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

SWISS:
Q9Y2S2

Gene ID:
51084

Database links:

Entrez Gene: 51084 Human

Entrez Gene: 68631 Mouse

Omim: 609877 Human

SwissProt: Q9Y2S2 Human

SwissProt: Q99KP3 Mouse

Unigene: 370703 Human



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