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Rabbit Anti-DDX24  antibody (bs-14219R)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
订购热线:400-901-9800
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-14219R
英文名称 DDX24
中文名称 ATP依赖解旋酶DDX24抗体
别    名 ATP dependent RNA helicase DDX24; ATP-dependent RNA helicase ddx24; DDX 24; ddx24; DDX24_HUMAN; DEAD (Asp Glu Ala Asp) box polypeptide 24; DEAD box protein 24; DEAD/H (Asp Glu Ala Asp) box polypeptide 24; S. cerevisiae CHL1 like helicase.  
研究领域 心血管  细胞生物  神经生物学  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Pig,Cow,Rabbit,Sheep)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 120kDa
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DDX24: 701-800/859 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level. [provided by RefSeq, Jul 2008]

Function:
ATP-dependent RNA helicase.

Tissue Specificity:
Ubiquitous. Most abundant in heart and brain, but with lowest levels in thymus and small intestine.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.

SWISS:
Q9GZR7

Gene ID:
57062

Database links:

Entrez Gene: 57062 Human

Entrez Gene: 27225 Mouse

Omim: 606181 Human

SwissProt: Q9GZR7 Human

SwissProt: Q9ESV0 Mouse

Unigene: 510328 Human

Unigene: 3935 Mouse

Unigene: 475067 Mouse



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