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Rabbit Anti-DLK2  antibody (bs-14342R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-14342R
英文名称 DLK2
中文名称 穿膜蛋白DLK2抗体
别    名 AI413481; Delta like 2 homolog; Delta like protein 2; delta-like 2 homolog (Drosophila); DLK 2; DLK-2; Dlk2; DLK2_HUMAN; EGF like domain containing protein 9; EGF like domain multiple 9; EGF-like protein 9; EGFL 9; EGFL9; Epidermal growth factor-like protein 9; MGC111055; MGC2487; Multiple EGF like domain protein 9; OTTHUMP00000016449; OTTHUMP00000016451; Protein delta homolog 2.  
研究领域 细胞生物  生长因子和激素  结合蛋白  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 38kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DLK2: 241-340/383 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 DLK2 is a 383 amino acid single-pass transmembrane protein with six tandem EGF-like repeats in the putative extracellular domain, which is characteristic of the EGF-like protein family. DLK2 shares nearly identical structural features with DLK, suggesting that it may function in a similar way. Like DLK, DLK2 affects adipogenesis of 3T3-L1 preadipocytes and mesenchymal C3H10T1/2 cells, yet it does so in an opposite way to that of DLK. Also, expression of DLK and DLK2 are inversely correlated and changes in expression of one gene will affect the expression levels of the other. Therefore, it is likely that adipogenesis is modulated by the coordinated expression of DLK and DLK2. There are two isoforms of DLK2 that are produced as a result of alternative splicing events.

Function:
Regulates adipogenesis.

Subcellular Location:
Membrane.

Similarity:
Contains 6 EGF-like domains.

SWISS:
Q6UY11

Gene ID:
65989

Database links:

Entrez Gene: 65989 Human

Entrez Gene: 106565 Mouse

SwissProt: Q6UY11 Human

SwissProt: Q8K1E3 Mouse

Unigene: 337251 Human

Unigene: 23633 Mouse



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