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Rabbit Anti-DNAH2  antibody (bs-14363R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-14363R
英文名称 DNAH2
中文名称 轴丝动力蛋白2抗体
别    名 axonemal; Axonemal beta dynein heavy chain 2; Ciliary dynein heavy chain 2; Dnah2; DYH2_HUMAN; Dynein heavy chain 2; Dynein heavy chain domain-containing protein 3.  
研究领域 细胞生物  信号转导  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Pig,Horse)
产品应用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 507kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNAH2: 3201-3300/4427 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH2 is an axonemal inner arm dynein heavy chain (Chapelin et al., 1997 [PubMed 9256245]).[supplied by OMIM, Mar 2008]

Function:
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly.

Subcellular Location:
Cytoplasm; cytoskeleton; cilium axoneme.

Tissue Specificity:
Expressed primarily in trachea and testis, 2 tissues containing axonemal structures. Also expressed in lung.

Similarity:
Belongs to the dynein heavy chain family.
Contains 5 TPR repeats.

SWISS:
Q9P225

Gene ID:
146754

Database links:

Entrez Gene: 146754 Human

SwissProt: Q9P225 Human

Unigene: 367649 Human



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