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Rabbit Anti-DNAJC14  antibody (bs-14381R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-14381R
英文名称 DNAJC14
中文名称 DNAJC14蛋白抗体
别    名 DJC14_HUMAN; DnaJ (Hsp40) homolog, subfamily C, member 14; DNAJ; DnaJ homolog subfamily C member 14; DnaJ protein homolog 3; DNAJC14; Dopamine receptor interacting protein; Dopamine receptor-interacting protein of 78 kDa; DRiP78; hDj 3; HDJ-3; HDJ3; Human DnaJ protein 3; LIP6; LYST interacting protein LIP6.  
研究领域 细胞生物  信号转导  转录调节因子  细菌及病毒  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Horse)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 79kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNAJC14: 151-250/702 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJC14 (DnaJ homolog subfamily C member 14), also known as DRIP78 (Dopamine receptor-interacting protein of 78 kDa) and HDJ3 (Human DnaJ protein 3), is a 702 amino acid endoplasmic reticulular membrane protein that contains one J domain. DnaJC14 regulates the export of target proteins, such as the dopamine D1 receptor (D1DR), from the endoplasmic reticulum to the cell surface.

Function:
Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Highly expressed in pancreas and selectively expressed in brain, lung, liver, skeletal muscle and kidney.

Similarity:
Contains 1 J domain.

SWISS:
Q6Y2X3

Gene ID:
85406

Database links:

Entrez Gene: 85406 Human

Entrez Gene: 74330 Mouse

Entrez Gene: 114481 Rat

Omim: 606092 Human

SwissProt: Q6Y2X3 Human

SwissProt: Q921R4 Mouse

SwissProt: Q5XIX0 Rat

Unigene: 709320 Human

Unigene: 296915 Mouse

Unigene: 114340 Rat



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