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Rabbit Anti-EPS8L1  antibody (bs-14616R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-14616R
英文名称 EPS8L1
中文名称 EPS8L1蛋白抗体
别    名 DRC 3; DRC3; Epidermal growth factor receptor kinase substrate 8 like protein 1; Epidermal growth factor receptor kinase substrate 8-like protein 1; Epidermal growth factor receptor pathway substrate 8 related protein 1; Epidermal growth factor receptor pathway substrate 8-related protein 1; EPS8 like 1; EPS8 like protein 1; EPS8-like protein 1; EPS8-related protein 1; EPS8L 1; EPS8L 1; Eps8l1; EPS8R1; ES8L1; ES8L1_HUMAN; FLJ20258; MGC23164; MGC4642; PP10566; PP10566.  
研究领域 细胞生物  信号转导  生长因子和激素  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog,Cow,Sheep,GuineaPig)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 80kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EPS8L1: 1-100/723 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.

Subunit:
Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Detected in placenta.

Similarity:
Belongs to the EPS8 family.
Contains 1 SH3 domain.

SWISS:
Q8TE68

Gene ID:
54869

Database links:

Entrez Gene: 54869 Human

Entrez Gene: 67425 Mouse

Entrez Gene: 361503 Rat

Omim: 614987 Human

SwissProt: Q8TE68 Human

SwissProt: Q8R5F8 Mouse

Unigene: 438862 Human

Unigene: 360392 Mouse

Unigene: 138370 Rat



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