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GTF2H3 Rabbit pAb (bs-16352R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-16352R
英文名称 GTF2H3 Rabbit pAb
中文名称 通用转录因子2H亚基3/TTFIIH p34抗体
别    名 Basic transcription factor 2 34 kDa subunit; BTF2; BTF2 p34; General transcription factor IIH polypeptide 3; General transcription factor IIH subunit 3; general transcription factor IIH, polypeptide 3, 34kDa; Gtf2h3; P34; TF2H3_HUMAN; TFB4; TFIIH; TFIIH b  
研究领域 细胞生物  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse,Chinese Hamster)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 34 kDa
检测分子量
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GTF2H3: 1-100/308 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core-TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14. [provided by RefSeq, Dec 2012]

Function:
Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Anchors XPB.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the TFB4 family.

SWISS:
Q13889

Gene ID:
2967

Database links:

Entrez Gene: 2967 Human

Entrez Gene: 511896 Cow

Entrez Gene: 100059174 Horse

Entrez Gene: 209357 Mouse

Entrez Gene: 288651 Rat

Omim: 601750 Human

SwissProt: Q05B56 Cow

SwissProt: Q13889 Human

SwissProt: Q8VD76 Mouse

SwissProt: Q561R7 Rat

Unigene: 355348 Human

Unigene: 185467 Mouse

Unigene: 203542 Rat



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