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ZRSR2 Rabbit pAb (bs-16408R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-16408R
英文名称 ZRSR2 Rabbit pAb
中文名称 ZRSR2蛋白抗体
别    名 CCCH type zinc finger, RNA binding motif and serine/arginine rich protein 2; MGC142014; U2AFM_HUMAN; MGC142040; Renal carcinoma antigen NY REN 20; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit related protein 2; U2(RNU2) small nuclear  
研究领域 细胞生物  免疫学  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human)
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 58 kDa
检测分子量
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZRSR2: 351-450/482 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. [provided by RefSeq, Jul 2008]

Function:
ZRSR2 is an essential splicing factor. The protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. This gene encodes U2AF small subunit related protein 2 which is an essential splicing factor. This protein is associated with the U2AF heterodimer composed of a large and a small subunit. It specifically interacts with the large subunit through an U2AF small subunit homologous region, and with SR proteins through its RS domain. This protein and U2AF small subunit are not functionally redundant.

Subunit:
Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Interacts (via RS domain) with SRSF1 and SRSF2. Interacts with U2AF2/U2AF65.

Subcellular Location:
Nuclear

Tissue Specificity:
Widely expressed.

Post-translational modifications:
Phosphorylated in the RS domain by SRPK1.

Similarity:
Contains 2 C3H1-type zinc fingers.
Contains 1 RRM (RNA recognition motif) domain.

SWISS:
Q15696

Gene ID:
8233

Database links:

Entrez Gene: 8233 Human

Entrez Gene: 22184 Mouse

Entrez Gene: 302670 Rat

Omim: 300028 Human

SwissProt: Q15696 Human

SwissProt: Q62377 Mouse

Unigene: 171909 Human

Unigene: 426178 Mouse

Unigene: 26786 Rat



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