| 产品编号 | bs-16886R |
| 英文名称 | KCNH5 |
| 中文名称 | KCNH5蛋白抗体 |
| 别 名 | EAG2; Ether a go go potassium channel 2; H EAG2; HGNC:6254; Kv10.2; potassium voltage gated channel subfamily H (eag-related) member 5; Voltage gated potassium channel subunit Kv10.2. |
| 研究领域 | 肿瘤 细胞生物 神经生物学 信号转导 通道蛋白 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human (predicted: Mouse,Rat,Dog,Pig,Cow,Horse,Sheep) |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 112kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KCNH5: 351-450/988 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. The KCNH5 gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. KCNH5 is not expressed in differentiating myoblasts. Subunit: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Heteromultimer with KCNH1/EAG (Probable). Subcellular Location: Cell Membrane: multi-pass membrane protein. Tissue Specificity: Detected in brain, skeletal muscle, heart,placenta, lung and liver, and at low levels in kidney. Similarity: Belongs to the potassium channel family. Contains 1 cyclic nucleotide-binding domain. Contains 1 PAS (PER-ARNT-SIM) domain. Contains 1 cyclic nucleotide-binding domain. ] Contains 1 PAS (PER-ARNT-SIM) domain. SWISS: Q8NCM2 Gene ID: 27133 Database links: Entrez Gene: 27133 Human Entrez Gene: 238271 Mouse Omim: 605716 Human SwissProt: Q8NCM2 Human SwissProt: Q6NZH0 Mouse SwissProt: Q920E3 Mouse Unigene: 27043 Human Unigene: 48753 Rat |
| 产品图片 |
Sample:
Hcclm3(Human) Cell Lysate at 30 ug Primary: Anti-KCNH5 (bs-16886R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 112 kD Observed band size: 117 kD 
Sample:
HepG2(Human) Cell Lysate at 30 ug Primary: Anti-KCNH5 (bs-16886R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 112 kD Observed band size: 117 kD |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
