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SIAT4A Rabbit pAb (bs-17483R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-17483R
英文名称 SIAT4A Rabbit pAb
中文名称 唾液酸转移酶4A抗体
别    名 3-GalNAc-alpha-2; 3-sialyltransferase 1; 3-sialyltransferase; 3-ST 1; alpha 2; alpha 23 ST; beta galactoside alpha 23 sialyltransferase; beta-galactoside alpha-2; beta-galactoside alpha-2, 3-sialyltransferase 1; CMP N acetylneuraminate beta galactosamide alpha 23 sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2; DKFZp666E036; DKFZp779K2051; FLJ36548; Gal beta 13 GalNAc alpha 23 sialyltransferase; Gal NAc6S; Gal-beta-1; Gal-NAc6S; MGC9183; OTTHUMP00000226912; OTTHUMP00000226913; SIA4A_HUMAN; Sialyltransferase 4A; SIAT4-A; SIAT4A; SIATFL; ST3Gal I; ST3GAL1; ST3GalA; ST3GalA.1; ST3GalI; ST3GalIA; ST3O.  
研究领域 细胞生物  免疫学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 39 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SIAT4A: 151-250/340 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008]

Function:
It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on sugar chains O-linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values.

Subcellular Location:
Golgi apparatus > Golgi stack membrane. Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.

Tissue Specificity:
Expressed in several tissues. Highest expression in lung, liver, skeletal muscle, kidney, pancreas, spleen and placenta.

Post-translational modifications:
The soluble form derives from the membrane form by proteolytic processing.

Similarity:
Belongs to the glycosyltransferase 29 family.

SWISS:
Q11201

Gene ID:
6482

Database links:

Entrez Gene: 6482 Human

Entrez Gene: 282351 Cow

Omim: 607187 Human

SwissProt: Q11201 Human

Unigene: 374257 Human



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