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Rabbit Anti-SIDT2  antibody (bs-17485R)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-17485R
英文名称 SIDT2
中文名称 SIDT2蛋白抗体
别    名 SIDT-2; B930096O19; BC023957; CGI 40; DKFZp686L17253; FLJ90656; MGC36407; MGC58967; RGD1308311; SID1 transmembrane family member 2; SID1 transmembrane family, member 2; SIDT2; SIDT2_HUMAN.  
研究领域 肿瘤  细胞生物  通道蛋白  跨膜蛋白  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human (predicted: Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep)
产品应用 WB=1:500-2000, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 93kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SIDT2: 201-300/832 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 SID-1 and SID-2 belong to the systemic RNA interference defective-1 (SID1) family of transmembrane proteins. SID-1, originally identified in C. elegans, is an 827 amino acid long protein. It localizes to the cell membrane and contains eleven transmembrane domains. This suggests that SID-1 possibly functions as a channel protein. The overexpression of SID-1 enhances double stranded RNA (dsRNA) uptake in pancreatic ductal adenocarcinoma cells. SID-2, also first identified in C. elegans, is an 832 amino acid long protein with multiple transmembrane domains. At least two isoforms exist for SID-2 due to alternative splicing. Isoform 2 contains an additional 21 amino acids after residue 387 and has an alternate sequence that is 8 amino acids shorter for residues 814 to 832 of isoform 1.

Subcellular Location:
Lysosome membrane.

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the SID1 family.

SWISS:
Q8NBJ9

Gene ID:
51092

Database links:

Entrez Gene: 51092 Human

Entrez Gene: 214597 Mouse

Entrez Gene: 315617 Rat

SwissProt: Q8NBJ9 Human

SwissProt: Q8CIF6 Mouse

SwissProt: D3ZEH5 Rat

Unigene: 712144 Human

Unigene: 379345 Mouse

Unigene: 162997 Rat



产品图片
Sample:
Panc-1(Human) Cell Lysate at 30 ug
Primary: Anti- SIDT2 (bs-17485R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 93 kD
Observed band size: 98 kD
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