| 产品编号 | bs-17618R |
| 英文名称 | SPAG11B |
| 中文名称 | 精子相关抗原11B抗体 |
| 别 名 | EP2; EP2C; EP2D; Epididymal protein 2; HE2; HE2C; Protein EP2; SPAG11; Sperm antigen HE2; Sperm associated antigen 11; Sperm associated antigen 11B. |
| 研究领域 | 细胞生物 发育生物学 细胞类型标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human) |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 9kDa |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SPAG11B: 41-103/103 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
SPAG11B is a 103 amino acid precursor protein that exists as four alternatively spliced isoforms, designated EP2A, EP2B, EP2C and EP2D, all of which are androgen-dependent, epididymis-specific secretory proteins that may play a role in sperm maturation and overall function. The gene encoding the SPAG11B precursor maps to a region on chromosome 8 that is near the ∫-defensin gene cluster and it is suggested that SPAG11B may exhibit functional characteristics (such as antimicrobial activity) that are similar to ∫-defensins. Human chromosome 8, on which the SPAG11B gene is localized, consists of nearly 146 million base pairs and houses more than 800 genes, some of which are associated with a variety of diseases and malignancies. Function: SPAG11B belongs to the SPAG11 family. The specific function of SPAG11B has not been determined, but it is thought to be involved in sperm maturation. It is specifically expressed in caput and proximal corpus of epididymis and is present in the epididymal epithelium and on the sperm surface, with a subacrosomal equatorial distribution on the sperm head. There are two named isoforms. Subcellular Location: Secreted Tissue Specificity: Specifically expressed in caput and proximal corpus of epididymis. Present in the epididymal epithelium and on the sperm surface, with a subacrosomal equatorial distribution on the sperm head. Similarity: Belongs to the SPAG11 family. SWISS: Q08648 Gene ID: 10407 Database links: Entrez Gene: 10407 Human SwissProt: Q08648 Human |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
